ASSOCIATION BETWEEN THE USE OF MEDICINES AND ADVERSE REACTIONS RELATED TO VACCINATION AGAINST COVID-19 IN RIO BRANCO, ACRE
Keywords:
SARS-CoV-2; Vaccines; Adverse reactions; self-medicationAbstract
COVID-19, originated by the new coronavirus SARS-CoV-2, has become a global pandemic. Despite the rapid development of vaccines against it, adverse reactions can occur and understanding individual responses and post-vaccination therapeutic decisions is essential. This study sought to evaluate the relationship between medications and reactions after vaccination in Rio Branco, Acre. The research involved 150 participants who received the 3rd or 4th dose of the COVID-19 vaccine. After vaccination, these participants were monitored by telephone for 30 days to check for any adverse reactions. Demographic data, information on adverse reactions after vaccination and use of medications associated with possible reactions to the vaccine were collected. Statistical analysis was represented by descriptive analysis and the association between variables and their influence according to the logistic regression model. The most common symptoms were local pain (42.9%), headache (22%), tiredness (8.8%) and fever (8.8%). Regarding gender, 42.9% of women and 44.1% of men reported pain at the application site. Furthermore, 8.7% chose anti-inflammatories and 6.5% used antibiotics after vaccination. Participants who experienced adverse reactions were almost 8 times more likely to resort to medication to relieve symptoms compared to those who did not experience such reactions (OR = 7.9895, p < 0.05). The significant association between adverse reactions and medication use highlights the importance of personalized and inclusive approaches to immunization against COVID-19, recognizing that different reactions can impact post-vaccination therapeutic choices.
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